The Case Study of Vanitas

It’s 19th-century Paris, and young vampire Noé hunts for the Book of Vanitas. Attacked by a vampire driven insane, a human intercedes, rescues Noé, and heals the sick creature. Commanding the book and calling himself Vanitas, this doctor tempts Noé with a mad crusade to “cure” the entire vampire race. Allying with one who wields arcane power so easily may be dangerous, but does he have a choice?

If you like this, try

Seraph of the End: Vampire Reign 81%

12 eps · 2015

You get another vampire-versus-human clash, though it trades Vanitas's gothic banter for grim shounen war stakes.

Black Butler 80%

24 eps · 2008

A darkly witty demon-and-human partnership set in old Europe mirrors the doctor-and-vampire dynamic you loved.

Moriarty the Patriot 80%

11 eps · 2020

Its brilliant, morally slippery mastermind scheming against a broken world feels like Vanitas's crusade with a detective-story polish.

Bungo Stray Dogs 79%

12 eps · 2016

A cursed protagonist adopted into a strange found-family of powers gives you that same tender-yet-dangerous alliance energy.